Friday, March 28, 2014

Dermatologic Treatments

Cooper University Hospital

Chemical Peels

Thousands of chemical peels are performed each year. Dermatologic surgeons have agents for the last 100 years and are experts in performing multiple types of chemical peels public's increasing interest in rejuvenating skin and slowing effects of the aging process which has emerged as an exciting supplement to a total skin care program. Dr. Lawrence will evaluate before embarking upon a chemical peel.

Indications
Melasma, Acne, Skin aging, sun damage, wrinkles (depends on peel solution)

Melasma is a brown discoloration of the face most often seen in women. This change can get worse in the summer when exposed to the sun's harmful rays and often fades. Pregnancy is the most common cause of melasma.

The Center for Dermatologic Surgery treats melasma with prescription bleaching topical in addition to a series of chemical peels. Since sunlight is a major factor in the melasma, it is imperative top continue to avoid the sun, wear protective clothing and apply sunscreen.

Benefits
  • Superficial: Freshens skin, makeup goes on nicer, may decrease some fine lines.
  • Medium Depth: Chemical peeling is often used to treat fine lines under the eye and mouth. Wrinkles caused by damage, aging, and hereditary factors can often be eliminated with this procedure. However, sags, bulges and more severe wrinkle peeling and may require other kinds of cosmetic surgical procedures. Dr. Lawrence determines the most appropriate treatment for your needs.
Mild scarring and certain types of acne can be treated with chemical peels. In addition, in the form of sun spots, age spots, liver spots, freckles, blotchiness, due to taking birth control that is dull in texture and color may be improved with chemical peeling . Areas of sun damage precancerous keratosis and scaling patches may improve after chemical peeling. Follow lesions or patches are less likely to appear.

Age spots, also known as sun spots, are flat, brown discoloration of the skin which usually is around the neck, hands, and other areas of the skin exposed to the sun over many years.

A German Study Underscores the Benfits Of Full-Body Screenings

Skin Cancer World News Round-Up
Skin Cancer Foundation Journal 2013


Since its inception in 1979, The Skin Cancer Foundation has recommended that everyone have an annual full-body skin exam performed by a physician. In 2012, A German skin cancer screening study- The largest ever conducted-found that regularly having total-body skin exams can cut melanoma deaths by more than 50 percent.
    Over the course of this year-long program in the German state of Schleswig-Holstein, doctors have found more melanomas than had been detected prior to the start of the program. This was not expected, since screenings typically lead to identification of greater numbers of skin cancers. What was more striking was how much earlier the melanomas were bring found. According to the researchers, this early identification slashed the melanoma death rate in half--very likely because tumors were thinner. As a general rule, the thinner the lesion, the easier to treat. Melanoma killed 43 men and 45 women in Schleswig-Holstein in the three years before the study, but just 23 men and 21 women in the post-study follow-up from 2006 to 2008.
    The results were so impressive that in 2008, Germany began a national skin cancer screening program, offering people ages 35 or older a total-body skin exam every two years. The authors suggested that such large-scale screening programs are feasible and advisable around the world, and have "the potential to reduce skin cancer burden, including mortality."

Tanning Machines Are Twice as Dangerous As the Midday Mediterranean Sun

Skin Cancer Foundation 2013

In their recent research into the dangers of ultraviolet (UV) tanning, British investigators didn't just crunch numbers. They also compared the "controlled dose" of UV radiation emitted by tanning machines with the intense midday Mediterranean sun -and refuted tanning salons operators' claims about the so-called "safety" of indoor tanning. The researchers found that the average indoor tanning machine in England is 2.3 times more cancer-causing than the midday Mediterranean sun, and some tanning machines are up to six times as dangerous. A 2003 study suggests that US tanning beds are about as dangerous as their English counterparts. Researchers determined that nine out of 10 tanning beds in England emit more UV radiation than recommended by British and European safety standards, typically, almost double the recommended amount. These excessive levels are especially worrisome considering that any UV tanning causes DNA damage that ages the skin and can ultimately cause skin cancers.

Thursday, March 6, 2014

The Best Sun Shield for Car, Home and Office

Window Film
Skin Cancer Foundation 2013

The Best Sun Shield for Car, Home and Office

Whether you're driving, at home gazing out at your garden, or sitting by a window at work, you actually may be suffering continual skin damage. While everyday windows block most of the sun/s ultraviolet B (UVB) rays, they allow much of its ultraviolet A (UVA) rays to pass right through. UVA penetrates deep into the skin, causing DNA damage that can accelerate skin aging and lead to skin cancer.
If you frequently sit by windows, the single best safeguard against UV damage is transparent window film, sometimes referred to as window tint, which has been treated to screen out both UVA and UVB rays. Installing protective film on your windows will keep you virtually UV-free on the road, at home, or at the office.

Curing Car Trouble
In cars, only the laminated windshield comes with both UVB and UVA protection. The side and back windows allow in more than 60 percent of UVA rays. Research has shown that UV damage is more extensive on the side of the body closer to the window; long-time drivers also have rougher, slacker, more wrinkled skin on their window side. Babies and young children — who have little protective skin pigment — often sit in back, where none of the glass (even darker glass found in SUVs and mini-vans) offers adequate UVA protection. Fortunately, UVA-filtering window film can go a long way to prevent skin damage. Combining UVA absorbers in varying strengths, the transparent films are available from clear to dark tints for vehicles’ side and back windows in all 50 states; it screens out more than 99 percent of UVA and UVB without reducing visibility.

  • Drivers in the US have more skin cancers on the left side of their faces: drivers in Australia have more skin cancers on the right.
Alternative Measures For Sun Protection While Driving
'It's wise to practice the following sun safety strategies everyday:
  • Cover up with clothing. Long-sleeve shirts help prevent UV damage to the drivers' window-side arm, and long pants protect your legs.
  • Use a broad spectrum (UVA/UVB) sunscreen with an SPF of 15 or higher. Don't forget often-missed spots like the top of the head, neck, hands and ears.
  • Take extra precautions in convertibles and cars with sunroofs. Wear a wide-brimmed hat and wraparound, UV-blocking sunglasses.
UV-absorbing auto window film reduces skin cell death 93 percent.

Sun Protection Indoors

Indoor workers stationed near windows have significantly more wrinkled, rough-textured, and sagging skin on the side of the face closer to the window.
Today, however, UV-screening residential and commercial film is available for home and office. UV absorbers are added to clear or tinted polyester or vinyl to create film, which comes in varied tints, allowing 30-80 percent of visible light to get through. The installers apply it on the interior glass surface of the windows from flat sheets.

Window film will help prevent sunburn and skin cancer, as well as the brief daily UV exposures that accelerate skin aging over time.


Chronic exposure to UVA rays through windows may accelerate skin aging by 5 to 7 years.

More than 90 percent of skin cancers and the visible signs of skin aging, are caused by the sun.

Advantages of Window Film
  • In hot weather, it cuts down heat within the vehicle or home, reducing air conditioning expenses.
  • In cold weather, some films reflect interior heat back into the house, reducing heating costs.
  • It helps keep sunshine from fading car upholstery and home furnishing.
UV-protective window film is available worldwide. For professional installation, look online or in the yellow pages under "glass tinting" or "glass coatings."

Several companies now carry The Skin Cancer Foundation's Seal Of Recommendation, offering assurance of safety and effectiveness.





 

 
    

Thursday, January 30, 2014

Skin Cancer Rates Soar in US Hispanics

Sun & Skin News
Skin Cancer Foundation
Winter 2013

Skin Cancer Rates Soar in US Hispanics

Skin cancer rates among Hispanics are skyrocketing in the US. New research shows that in the past two decades alone, melanoma incidence among Hispanics has risen almost 20 percent.
Hispanics are the fastest-growing population in the US, with a 43 percent increase in their numbers from 2000 to 2010. It is estimated that by 2050, the Hispanic population will exceed 100 million, representing more than 24 percent of the total population. Unfortunately, as the number of Hispanics has risen, so have their instances of skin cancer: From 1992 to 2008, their annual melanoma incidence increased by 19 percent. Too little use of sun safety techniques (such as seeking shade, wearing protective clothing, and using sunscreen) may have contributed to this rapid rise in melanoma and other skin cancers among Hispanics.

The Risk Is Real
One reason for this underuse of sun protection strategies may be the widespread misconception that people with darker skin are not at risk of skin cancer, according to a recent survey by L’Oreal Paris. Other studies point to the lack of skin cancer education campaigns provided for Hispanics and the need for their dermatologists and general physicians to emphasize skin cancer dangers. The authors of a study published this June in JAMA Dermatology said their findings highlighted “the importance of developing culturally appropriate, tailored interventions to reduce the risk of skin cancer among Hispanics.” These studies all concluded that raising awareness among Hispanics will save lives. Culturally sensitive materials, customized interventions, and stronger public health messages were all suggested as ways to combat the growing skin cancer epidemic among Hispanics.

Deadly Results
Making matters worse for Hispanics, those with melanoma have poorer survival than non-Hispanic patients, often due to being diagnosed at a later stage. One study in JAMA Dermatology found that while initial melanoma diagnoses were late-stage in 16 percent of white patients, the number jumped to 26 percent for Hispanics. This trend towards later diagnosis among Hispanics reinforces the need for greater skin cancer education and awareness. These findings underscore the urgency for year-round sun protection, regular skin self-examinations, and annual visits to a dermatologist for everyone, no matter what their ethnicity or skin tone.



BCC or SCC? The Value of Pain
Pain is a potential diagnostic tool for non-melanoma skin cancers. In a study from Wake Forest University Baptist Medical Center in North Carolina, squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) patients reported fairly comparable levels of itching at the cancer site. However, a far higher percentage of SCC patients (39 percent) than BCC patients (17 percent) reported pain at the tumor site. Thus, pain may be an important factor distinguishing the two cancers. Left untreated, SCC, in particular, can be fatal: About two percent of SCC patients—between 3,900 and 8,800 people—died from the disease in the US in 2012. It is therefore vital for dermatologists to differentiate SCC from BCC early in the lesion’s development to determine the best treatment.

Percentage of patients reporting itching or pain as a symptom
Dangerous Tanning Habits Persist in Young Women

Despite the now well-established dangers of indoor tanning, teenage and young adult women continue to use tanning beds at an alarming rate, according to the Centers for Disease Control and Prevention’s recent survey study of more than 15,000 subjects. In the 12 months before being surveyed, the study found:

  • Over 29 percent of non-Hispanic white female high school students engaged in indoor tanning at least once, and almost 17 percent did so at least 10 times.
  • Nearly 25 percent of non-Hispanic white women ages 18 to 34 engaged in indoor tanning at least once, and over 15 percent did so at least 10 times.
These findings reinforce past research, notes California dermatologist Melanie Palm, MD, spokeswoman for The Skin Cancer Foundation. “A disproportionate number of girls and young women use tanning beds,” she says. “There’s a cultural disconnect between the risk and the desire for a ‘healthy glow.’”
       The new study’s findings highlight the need for greater understanding among young women about the dangersof indoor tanning. Since physical appearance may mean more to them than long-range health effects, the study authors advise making teenagers and young adults aware that tanning causes not just skin cancer, but age spots, wrinkling, and other negative cosmetic affects. The FDA is also working to help solve the problem: in March 2013 it issued a proposal to raise the classification of tanning beds from Class 1 (low to moderate risk) devices to Class II (moderate to high risk) devices; that proposal is currently under review.
        The Skin Cancer Foundation recommends that people of all ages, genders, and ethnic backgrounds avoid indoor tanning and take precautions in the sun by limiting outdoor time between 10 am and 4 pm, seeking the shade when outdoors, using SPF 15+ sunscreen (SPF 30+ sunscreen for extended stays outdoors), and wearing protective clothing, including wide-brimmed hats and UV-blocking sunglasses.



New Breakthroughs In Melanoma Treatment
Two new oral drugs, dabrafenib (TafinlarTM) and trametinib (MekinistTM), have been FDA approved for stage IV melanoma patients. Like its predecessor vemurafenib, dabrafenib inhibits a defective gene called BRAF, thereby slowing or stopping production of melanoma cells. Trametinib is the first drug to inhibit another defective gene, MEK, also slowing or stopping production of melanoma cells. Both medicines have been found to hold back disease progression and increase survival by months or even years, and even greater results are expected when they are tried in combination with other drugs.

2013 Road to Healthy Skin Tour: More Skin Cancers Found, More Lives Saved
 
The Skin Cancer Foundation’s annual Road to Healthy Skin Tour, presented by Rite Aid, has wrapped up its sixth cross country journey, bringing free skin cancer screenings and prevention information to communities across America.
Over a four-month period, the 2013 Tour traveled 14,000 miles and held 53 events in 13 states. Seventy dermatologists donated their time to perform exams in the Tour’s customized 38-foot RV, equipped with two private exam rooms.
During this year’s Tour, volunteer dermatologists detected 788 suspected precancers and cancers, including 29 suspected melanomas. Since 2008, the Foundation’s volunteer dermatologists have potentially saved 324 lives; 324 melanomas have been detected since the Tour began. By finding suspected skin cancers, often in early stages, the Tour and its volunteer dermatologists have made a vital contribution to communities across the country.


A Message From the President

    With winter just around the corner, do we still have to worry about skin cancer prevention? In a word—yes. While the sun’s ultraviolet B (UVB) rays (the sunburn-causing rays) are strongest in summer, UVA rays remain constant throughout the year. UVA can penetrate into deeper layers of the skin, causing wrinkles, brown spots, and other signs of skin aging. It also can cause skin cancer.
     Winter vacations add to your skin hazards. Snow and ice reflect up to 80 percent of UV rays, meaning that the rays hit you a second time. Furthermore, at higher altitudes (if you’re skiing in the mountains, for example), UV radiation exposure increases 4 to 5 percent with every 1,000 feet above sea level. Even in winter outerwear, your face and neck—where the majority of skin cancers occur—remain at least partially exposed. If you vacation in a sunny climate this winter, beware—intense sun exposure, the kind of exposure that typically leads to sunburn on a sunny vacation, greatly increases your risk of developing melanoma.
With these risks in mind, here are some key items you’ll need to stay sun-safe this winter:
Sun-protective clothing: Long sleeves, long pants, and gloves not only keep you warmer, but protect your arms, legs and hands against UV. A winter hat also pulls double duty, keeping your head warm and protecting your scalp, ears, and part of your face from the sun.
Sunglasses: Skin cancers of the eyelids account for 5-10 percent of all skin cancers, so sunglasses are essential. Look for a pair that locks 99-100 percent of UV rays, in a wraparound style that also offers protection on the sides. Try them on in the store to ensure a close fit so they don’t end up slipping down your nose, allowing UV rays to creep in.
Sunscreen: Clothing doesn’t protect all of your face, so keep a bottle of broadspectrum (UVA/UVB) sunscreen with an SPF of 15 or higher (SPF 30+ for extended outdoor exposure) where you’ll remember to use it all winter. Additionally, a significant percentage of all cancers are on the lips, so use a lip balm with a comparable SPF.
       One thing not to do when the weather turns cold is turn to tanning beds. Recent research shows that more than 170,000 cases of non-melanoma skin cancer in the US each year are linked to indoor tanning. If you simply must have darkened skin, use a self-tanning product. Better yet, embrace the healthy, natural glow and radiance of your own skin. Remember to protect your skin throughout winter—while driving, playing with your children, skiing, or shoveling snow. Even though the seasons are changing, your commitment to skin cancer prevention should remain the same.


By Laurie Jacobson,MD
Laurie Jacobson, MD is a fellowship-trained Mohs surgeon and a member of the American College of Mohs surgery, Dr. Jacobson practices in Seattle, WA. She specializes in Mohs surgery, dermatologic and laser surgery, cosmetic surgery and skin cancer surveillance. Dr. Jacobson has authored textbook chapters and published widely in peer-reviewed journals. She is contributing editor for the peer-reviewed journal Dermatologic Surgery.

Q: Why is seeing a dermatologist for annural skin screening so important?
A. An early skin cancer diagnosis can be the difference between life and death. Early-stage skin cancers are almost always curable; those found later are harder to treat.

Q: Will have to undress completely? What does a full body exam entail?
A. You will fully undress but wear a gown. Ask a nurse or assistant to be present if you’re uncomfortable undressing with just your doctor in the room. Sometimes my patients leave socks on, or have their hair in an up-do where I can’t access their scalp. But you can develop skin cancer anywhere you have skin—between toes, behind your ears, on your buttocks, groin, or genitalia. Women should not wear makeup or nail polish to the appointment. Wear your hair loose so that your doctor can access your scalp. Your visit should take 15 to 20 minutes. The doctor will examine each part of your skin, and may use a special magnifying glass with a light—called a dermatoscope—to examine certain marks or lesions.

Q: What questions will I be asked?
A. The doctor will want to know if you or any close family members have a history of skin cancer, which would increase your risk of developing the disease. You might also be asked if you’ve ever used tanning beds and how frequently, as well as how regularly you use sunscreen and other sun protection. You might be asked what medications you take, since some increase sun sensitivity and sunburn risk, or suppress the immune system, predisposing you to skin cancer. The more honest you are, the more you’ll get out of your exam.

Q: What happens if the doctor sees something out of the ordinary? Will he/she automatically do a biopsy?
A. When you come for your exam, be prepared for the possibility of a biopsy that day. It’s a quick, simple procedure. We use local anesthetic and take a small tissue sample, which is then examined under a microscope. The purpose is to diagnose the condition, not treat it, so once the biopsy site heals up, if the biopsy revealed skin cancer, the remainder of the growth will beremoved. If any atypical cells are found, they will be removed if deemed necessary, or the doctor might photograph them and have you come back weeks or months later to see if they have grown or changed in any way. 

Q: What can I do at home to make sure I catch skin cancers early?
A. We recommend that you perform a self-skin check once a month to look for any new or changing moles or marks. Have a partner help if possible: my friend’s nine-year-old daughter helped her examine her back, and discovered a basal cell carcinoma.
       Learn more about self-skin exams at SkinCancer.org/selfexam.


Monday, October 21, 2013

A Cure For The Wondering Eye

The Week

Taking a common antibiotic can help men resist the allure of attractive women, Nature reports. Researchers recruited 100 men and gave half of them a course of minocycline, an antibiotic used to treat acne that also appears to improve decision-making. Then they asked them to play a game of trust, in which the men had to decide how much money to give a women of varying attractiveness, knowing that some women could opt to keep it all while others would give back triple what they got. The men who weren't taking minocycline acted like typical men, giving more money to the women they considered highly attractive; the men on the antibiotic treated all the women the same. That suggests minocycline may disrupt the tendency of men to lavish attention and gifts on pretty women in order to seduce them and "increase the probability of producing attractive offspring," the study authors say. For unexplained reasons, minocycline seems to affect the brain, improving focus and mood.

Friday, October 18, 2013

Sleep deprivation linked to skin aging

Medical New Today

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals (UH) Case Medical Center found that sleep quality impacts skin function and aging. The recently completed study, commissioned by Estee Lauder, demonstrated that poor sleepers had increased signs of skin aging and slower recovery from a variety of environmental stressors, such as disruption of the skin barrier or ultraviolet (UV) radiation. Poor sleepers also had worse assessment of their own skin and facial appearance.
The research team, led by Primary Investigator Elma Baron, MD, presented their data this spring at the International Investigative Dermatology Meeting in Edinburgh, Scotland in an abstract titled "Effects of Sleep Quality on Skin Aging and Function."
"Our study is the first to conclusively demonstrate that inadequate sleep is correlated with reduced skin health and accelerates skin aging. Sleep deprived women show signs of premature skin aging and a decrease in their skin's ability to recover after sun exposure," said Dr. Baron, Director of the Skin Study Center at UH Case Medical Center and Associate Professor of Dermatology at Case Western Reserve University School of Medicine. "Insufficient sleep has become a worldwide epidemic. While chronic sleep deprivation has been linked to medical problems such as obesity, diabetes, cancer and immune deficiency, its effects on skin function have previously been unknown."
Skin functions as an important barrier from external stressors such as environmental toxins and sun-induced DNA damage. The research team set out to determine if skin function and appearance is also impacted by sleep quality, which is vital to the growth and renewal of the body's immune and physiological systems.
The study involved 60 pre-menopausal women between the ages of 30 and 49, with half of participants falling into the poor quality sleep category. The classification was made on the basis of average duration of sleep and the Pittsburgh Sleep Quality Index, a standard questionnaire-based assessment of sleep quality. The study involved a visual skin evaluation and participation in several non-invasive skin challenge tests including UV light exposure and skin barrier disruption. Additionally, participants filled out a sleep log for one week to quantify sleep duration.
The researchers found statistically significant differences between good and poor quality sleepers. Using the SCINEXA skin aging scoring system, poor quality sleepers showed increased signs of intrinsic skin aging including fine lines, uneven pigmentation and slackening of skin and reduced elasticity. In this system, a higher score means a more aged appearance. The average score in the good quality sleepers was 2.2 versus 4.4 in poor quality sleepers. They found no significant difference between the groups in signs of extrinsic aging, which are attributed primarily to sun exposure, such as coarse wrinkles and sunburn freckles.
The researchers found that good quality sleepers recovered more efficiently from stressors to the skin. Recovery from sunburn was more sluggish in poor quality sleepers, with erythema (redness) remaining higher over 72 hours, indicating that inflammation is less efficiently resolved. A Transepidermal Water Loss (TEWL) test was used at various time points to determine the ability of the skin to serve as an effective barrier against moisture loss. In measurements 72 hours after a skin barrier stressor (tape-stripping), the recovery of good quality sleepers was 30% higher than poor quality sleepers (14% vs. -6%) demonstrating that they repair the damage more quickly.
Additionally, poor quality sleepers were significantly more likely to have a higher Body Mass Index (BMI). For example, 23% of good quality sleepers were obese compared to 44% of poor quality sleepers. Not surprisingly, self perception of attractiveness was significantly better in good quality sleepers (mean score of 21 on self evaluation) vs. poor quality sleepers (mean score of 18).
"This research shows for the first time, that poor sleep quality can accelerate signs of skin aging and weaken the skin's ability to repair itself at night," said Dr. Daniel Yarosh, Senior Vice President, Basic Science Research, R&D, at The Estée Lauder Companies. "These connections between sleep and skin aging, now supported with solid scientific data, will have a profound effect on how we study skin and its functions. We see these findings as yet another way we can direct our scientific research toward the real needs of our customers who want to look and feel their best."